July 21, 2019

In 2009 the United States National Institute of Mental Health (NIMH) introduced the Research Domain Criteria (RDoC) project, which intends to explicate fundamental bio-behavioral dimensions that cut across heterogeneous disorder categories in psychiatry. One major research domain is defined by arousal and regulatory systems. In this study we aimed to investigate the relation between arousal systems (EEG-beta phenotypes also referred to as spindling excessive beta (SEB), beta spindles or sub-vigil beta) and the behavioral dimensions: insomnia, impulsivity/ hyperactivity and attention. This analysis is conducted within a large and heterogeneous outpatient psychiatric population, in order to verify if EEG-beta phenotypes are an objective neurophysiological marker for psychopathological properties shared across psychiatric disorders.

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